amitriptyline dog::All three had been unsuccessfully treated with conventional analgesics, including nonsteroidal antiinflammatory drugs, glucocorticoids and opiate agonists, prior to referral, with minimal or no response amitriptyline dog

amitriptyline dog::All three had been unsuccessfully treated with conventional analgesics, including nonsteroidal antiinflammatory drugs, glucocorticoids and opiate agonists, prior to referral, with minimal or no response.
They were investigated by neurological examination plus conventional ancillary diagnostic tests and therapeutic drug trials.
Ruling out other causes of pain and applying previously welldescribed criteria, each case was diagnosed as consistent with neuropathic pain, a poorly recognised condition in domestic dogs.
Treatment with the tricyclic antidepressant drug, amitriptyline, or the antiepileptic drug, gabapentin, resulted in either a dramatic improvement or full resolution of clinical signs in all cases.